Identifying and Appraising Knowledge Graphs for Hospital Information Systems

Authors

  • Subhodip Mitra All India Institute of Medical Sciences, Mangalagiri, India Author
  • Vikas Karamchand Dagar All India Institute of Medical Sciences, Kalyani, India Author
  • Rashmi Ranjan Guru All India Institute of Medical Sciences, Jodhpur, India Author
  • Bhukya Subhash All India Institute of Medical Sciences, Kalyani, India Author

DOI:

https://doi.org/10.68337/cpsm.v1.i1.2026-006

Keywords:

Knowledge graphs, hospital information systems, clinical decision support, data interoperability, semantic web, healthcare ontologies

Abstract

Hospital information systems (HIS) collect and store large amounts of clinical, administrative, and operational data from many sources. However, integrating these data across departments and making them interoperable remain difficult. Recent research has turned to knowledge graphs (KGs), which organize different types of healthcare data semantically and can support clinical decision-making, workflow optimization, and data exchange between systems. This article identifies and appraises existing KG applications in HIS on the basis of recent peer-reviewed literature. It surveys the implementation frameworks, ontological models, and integration architectures that researchers have adopted in hospitals, and it evaluates how well they address semantic heterogeneity, data silos, and real-time decision-making. The findings show that KGs have great potential in hospitals, but several barriers stand in the way of their adoption in the health information ecosystem, among them limited scalability, the lack of standardization of operational data, and low institutional readiness.

References

[1] Bilal Abu-Salih, Muhammad AL-Qurishi, Mohammed Alweshah, Mohammad AL-Smadi, Reem Alfayez, and Heba Saadeh, "Healthcare knowledge graph construction: A systematic review of the state-of-the-art, open issues, and opportunities," J. Big Data, vol. 10, no. 1, Art. no. 81, 2023, doi: 10.1186/s40537-023-00774-9.

[2] Shelly Sachdeva and Subhash Bhalla, "Using knowledge graph structures for semantic interoperability in electronic health records data exchanges," Information, vol. 13, no. 2, Art. no. 52, 2022, doi: 10.3390/info13020052.

[3] Hassan S. Al Khatib, Subash Neupane, Harish Kumar Manchukonda, Noorbakhsh Amiri Golilarz, Sudip Mittal, Amin Amirlatifi, and Shahram Rahimi, "Patient-centric knowledge graphs: A survey of current methods, challenges, and applications," Front. Artif. Intell., vol. 7, Art. no. 1388479, 2024, doi: 10.3389/frai.2024.1388479.

[4] Lino Murali, G. Gopakumar, Daleesha M. Viswanathan, and Prema Nedungadi, "Towards electronic health record-based medical knowledge graph construction, completion, and applications: A literature study," J. Biomed. Inform., vol. 143, Art. no. 104403, 2023, doi: 10.1016/j.jbi.2023.104403.

[5] Hao Yang, Jiaxi Li, Chi Zhang, Alejandro Pazos Sierra, and Bairong Shen, "Large language model-driven knowledge graph construction in sepsis care using multicenter clinical databases: Development and usability study," J. Med. Internet Res., vol. 27, Art. no. e65537, 2025, doi: 10.2196/65537.

[6] Yong Shang, Yu Tian, Kewei Lyu, Tianshu Zhou, Ping Zhang, Jianghua Chen, and Jingsong Li, "Electronic health record-oriented knowledge graph system for collaborative clinical decision support using multicenter fragmented medical data: Design and application study," J. Med. Internet Res., vol. 26, Art. no. e54263, 2024, doi: 10.2196/54263.

[7] Yanjun Gao, Ruizhe Li, Emma Croxford, John Caskey, Brian W. Patterson, Matthew Churpek, Timothy Miller, Dmitriy Dligach, and Majid Afshar, "Leveraging medical knowledge graphs into large language models for diagnosis prediction: Design and application study," JMIR AI, vol. 4, Art. no. e58670, 2025, doi: 10.2196/58670.

[8] Parinaz Tabari, Gennaro Costagliola, Mattia De Rosa, and Martin Boeker, "State-of-the-art Fast Healthcare Interoperability Resources (FHIR)-based data model and structure implementations: Systematic scoping review," JMIR Med. Inform., vol. 12, Art. no. e58445, 2024, doi: 10.2196/58445.

[9] Hejie Cui, Jiaying Lu, Ran Xu, Shiyu Wang, Wenjing Ma, Yue Yu, Shaojun Yu, Xuan Kan, Chen Ling, Liang Zhao, Zhaohui S. Qin, Joyce C. Ho, Tianfan Fu, Jing Ma, Mengdi Huai, Fei Wang, and Carl Yang, "A review on knowledge graphs for healthcare: Resources, applications, and promises," J. Biomed. Inform., vol. 169, Art. no. 104861, 2025, doi: 10.1016/j.jbi.2025.104861.

[10] Marvin Hofer, Daniel Obraczka, Alieh Saeedi, Hanna Köpcke, and Erhard Rahm, "Construction of knowledge graphs: Current state and challenges," Information, vol. 15, no. 8, Art. no. 509, 2024, doi: 10.3390/info15080509.

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Published

2026-09-30 — Updated on 2026-10-01

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Data Availability Statement

The data supporting the findings of this study are available from the corresponding author upon reasonable request.

How to Cite

Identifying and Appraising Knowledge Graphs for Hospital Information Systems. (2026). Conference Proceedings in Science and Management, 1(1), 23-27. https://doi.org/10.68337/cpsm.v1.i1.2026-006 (Original work published 2026)